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Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used…

4th Annual CTMR Symposium December 4th 2023!

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Save the date for our 4th annual UW Center for Translational Muscle Research (CTMR) symposium.  This year the symposium will be an all-day event on Monday, December 4th, 2023 in Seattle, WA at Orin Smith Auditorium.   We are planning to have an in-person symposium but will also have a Zoom-in option.   Our Keynote speakers this year will be: Douglas Millay, PhD, is a faculty member…

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CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…

CTMR represents at the 50th European Muscle Conference Florence 2023

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Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…

CTMR Pilot Grant Recipient Dr. Farid Moussavi-Harami awarded NIH R01 Grant

CTMR Pilot Grant Recipient Dr. Farid Moussavi-Harami awarded NIH R01 Grant

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A huge congratulations to 2020 CTMR pilot grant recipient Farid Moussavi-Harami, MD, who recently received a Notice of Award for his first NIH R01 grant! An Assistant Professor with the UW Medicine’s Division of Cardiology, Dr. Moussavi Harami’s CTMR pilot grant study focused on the genetic mutations, such as dilated cardiomyopathy, impacted contractile force in…