2022 Myofilament Meeting

Byctmr1 June 23, 2022June 23, 2022

In May, CTMR Investigators participated in the 2022 Myofilament research conference “Myofilament Form and Function: Determinants of Sarcomeric Contractility” in Madison, Wisconsin.

Saffie Mohran presented “Embryonic myosin mutations T178I & R672C result in mechanical and structural dysfunction in hPSC derived skeletal muscle”.

Farid Mousseri-Harami presented “Dancamtiv reversed negative effects on cardiac myofilament function in the I61Q cTnC mouse model of dilated cardiomyopathy”.

CTMR represents at the 50th European Muscle Conference Florence 2023
Bykd August 15, 2023August 15, 2023

Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…

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Congratulations to our 2021 Pilot Grant Program Awardees
Byctmr1 May 27, 2021November 21, 2024

The UW Center for Translational Muscle Research (CTMR) is delighted to announce that three exciting pilot grants have been awarded as part of the 2021 Pilot Grant Program. The CTMR Pilot Grant Program provides funding to support the development of exciting new muscle research on campus by allowing investigators to (1) obtain preliminary data needed…

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Congratulations to CTMR Team Core D for their JGP May cover
Bykd June 15, 2023April 20, 2026

Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used…

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ISCRM- “Spirit of Collaboration Fuels Momentum in Muscle Research”
Bykd October 4, 2022October 4, 2022

Momentum in Muscle Research

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Eesha Murali was awarded a Washington Research Foundation fellowship!
Bykd October 10, 2022November 21, 2024

Please join us in congratulating Eesha Murali on her Washington Research Foundation (WRF) Fellowship!

Read More Eesha Murali was awarded a Washington Research Foundation fellowship!
Bykd February 6, 2023February 6, 2023

CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…

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