Accelerating and expanding translational muscle research

The UW Center for Translational Muscle Research (CTMR) is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to provide a unifying organization for muscle research in the heart of Seattle’s biomedical research community.  The goal of the Center is to facilitate new collaborations, recruit new investigators, bring clinicians and researchers together, and provide access to state-of-the-art approaches in multi-scale biomechanics, metabolism, and quantitative-computational analysis, to accelerate translational research efforts at the UW.

Latest News:

Molecular model of myosin.

New Grants Power Muscle Science

Two new grants will accelerate atomic-scale research into the molecular mechanisms of cardiomyopathies. In Autumn 2024, CTMR investigator Matthew Childers was awarded a competitive K99/R00 Pathway to Independence Award from…

CTMR to Host Distinguished Lecturer Dr. Jonathan Kirk

CTMR to Host Distinguished Lecturer Dr. Jonathan Kirk

The CTMR is thrilled to host Dr. Jonathan Kirk, Professor and Vice Chair at the Stritch School of Medicine Cell & Molecular Physiology, Loyola University of Chicago on: April 24,…

Engineering heart health- featuring CTMR investigators

Engineering heart health- featuring CTMR investigators

The remarkable research of CTMR faculty was recently featured on the UW College of Engineering homepage! Read the full story here: Engineering heart health. Congratulations to the Sniadecki, Davis, and Regnier…

CTMR is Transitioning to Bluesky

CTMR is Transitioning to Bluesky

The CTMR is transitioning from X (Twitter) to Bluesky. Follow us on Bluesky at: https://bsky.app/profile/ctmr-uw.bsky.social Our X (Twitter) account will be closed at the end of January.

The CTMR was Renewed!

The CTMR was Renewed!

We are thrilled to share that the CTMR was RENEWED! Here’s to another 5 years of supporting muscle research translational muscle research!

Upcoming Events:

Online bi-weekly seminar series, Thursdays 8-9 am Pacific Time, covering current state-of-the-art research related to sarcomere structure and function.

To Subscribe to the Sarcomere Society email list and receive Zoom links to attend please click here.

Contact the Sarcomere Society Speaker Selection Committee – Drs Matt Childers & Joe Powers – to let us know about exciting new research you would like to present at an upcoming seminar (mcc7fb@uw.edu or powersjd@uw.edu)

Mar 13, 2025

Speaker: Dr. Natalia Koubassova, Professor, Institute of Mechanics, Lomonosov Moscow State University

Talk Title: Annotating the X-ray diffraction pattern of vertebrate striated muscle

Mar 27, 2025

Speaker: Dr. Daniel Fitzsimons, Department of Animal, Veterinary, and Food Sciences at the University of Idaho

Talk Title: Examining contractile dynamics in the mammalian heart

Apr 10, 2025

Speaker: Dr. Anne Houdusse -Juille, Cell biology and Cancer Department – institut Curie Paris France

Talk Title: Myosin Conformational Dynamics Modulate Cardiac Output in Disease and Therapy

The International Sarcomere Society Seminar Series was founded by Drs. Mike Regnier, Mike Geeves, and Bill Lehman.

Resource Cores

Mechanics & Devices Core

The Mechanics and Devices Core provides state-of-the-art measurements of muscle biomechanics at multiple levels of integration, and develops new assays for maturation and assessment of early stage muscle.

Metabolism Core

The Metabolism Core provides tools for in-depth measures and analysis of metabolomics, energetics, cell respiration and mitochondrial function.

Quantitative Analysis Core

The Quantitative Analysis Core provides computational and statistical tools for understanding disease, suggesting new
therapeutic targets, and understanding mechanisms.