Accelerating and expanding translational muscle research
The UW Center for Translational Muscle Research (CTMR) is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to provide a unifying organization for muscle research in the heart of Seattle’s biomedical research community. The goal of the Center is to facilitate new collaborations, recruit new investigators, bring clinicians and researchers together, and provide access to state-of-the-art approaches in multi-scale biomechanics, metabolism, and quantitative-computational analysis, to accelerate translational research efforts at the UW.
Latest News:
CTMR is Transitioning to Bluesky
The CTMR is transitioning from X (Twitter) to Bluesky. Follow us on Bluesky at: https://bsky.app/profile/ctmr-uw.bsky.social Our X (Twitter) account will be closed at the end of January.
The CTMR was Renewed!
We are thrilled to share that the CTMR was RENEWED! Here’s to another 5 years of supporting muscle research translational muscle research!
Muscle Myosin Makes a Halloween Debut Thanks to CTMR Postdoc Christian Mandrycky!
Dr. Christian Mandrycky, a postdoc jointly mentored by CTMR Investigators Mike Regnier & David Mack, was invited to present his work at the Cardiovascular Biology Breakfast Club Seminar Series on…
Come work with us!
Please see the below descriptions of 3 excellent, available postdoc positions in CTMR Investigator Labs. Please consider applying and/or share with your networks! The Regnier Lab invites applications for a…
Multiscale collaboration leads to monumental multiscale modeling
How individuals, labs, centers, and institutions collaborated to produce the first ever computational model showing changes at the protein level manifesting at the protein, sarcomere, cell, tissue, and organ level.…
Upcoming Events:
Sarcomere Society:
Online bi-weekly seminar series, Thursdays 8-9 am Pacific Time, covering current state-of-the-art research related to sarcomere structure and function.
To Subscribe to the Sarcomere Society email list and receive Zoom links to attend please click here.
Contact the Sarcomere Society Speaker Selection Committee – Drs Matt Childers & Joe Powers – to let us know about exciting new research you would like to present at an upcoming seminar (mcc7fb@uw.edu or powersjd@uw.edu)
Dec 5, 2024
Speaker: Dr. Irene Pertici, PhysioLab, Department of Biology, University of Florence
Talk Title: In vitro half-sarcomere mechanics
Dec 19, 2024
Speaker: Dr. Christopher Solís, Assistant Professor, Department of Health, Nutrition, and Food Sciences, Florida State University
Talk Title: Mechanisms of (dis)assembly of Cardiac Muscle Sarcomeres: Zooming Into the Z-Disc Proteins
Jan 9, 2025
Speaker: Dr. Luca Fusi, Lecturer in Muscle Physiology, Centre for Human and Applied Physiological Sciences, King’s College London
Talk Title: Investigating the regulation of the myosin motors in thick-filament domains in single myofibrils
The International Sarcomere Society Seminar Series was founded by Drs. Mike Regnier, Mike Geeves, and Bill Lehman.
Resource Cores
Mechanics & Devices Core
The Mechanics and Devices Core provides state-of-the-art measurements of muscle biomechanics at multiple levels of integration, and develops new assays for maturation and assessment of early stage muscle.
Metabolism Core
The Metabolism Core provides tools for in-depth measures and analysis of metabolomics, energetics, cell respiration and mitochondrial function.
Quantitative Analysis Core
The Quantitative Analysis Core provides computational and statistical tools for understanding disease, suggesting new
therapeutic targets, and understanding mechanisms.