The UW Center for Translational Muscle Research was proud to be a co-sponsor of the 2024 Myofilament Meeting [link] in Madison, WI. CTMR members Mike Regnier, Matt Childers, and Travis Tune presented research updates and led topical workshops on modeling myofilament diseases using iPSC-derived cardiomyocytes and computational methods. Workshop | May 21, 2024: This workshop…
The CTMR is thrilled to host Dr. Steve Schwartz, Regents Professor of Chemistry and Biochemistry at the University of Arizona at today’s Cardiovascular Biology Breakfast Club seminar series. Dr. Schwartz shares his work on: Theoretical studies of the cardiac thin and thick filament- Structure, the allosteric transmission of mutation and drug mechanism.
5th Annual CTMR Symposium WHEN: November 12, 2024, 9:00AM – 6:30PM PT WHERE: UW South Lake Union (SLU) campus (850 Republican St., Seattle, WA, 98109), C Building, Orin Smith Auditorium Please join us for an exciting day of science including a Keynote Session with investigators from the Study of Muscle, Mobility, and Aging (SOMMA), a Featured Research…
We are thrilled to invite you to register for our 5th Annual CTMR Symposium! We hope you can join us for an exciting day of science including a Keynote Session with investigators from the Study of Muscle, Mobility, and Aging (SOMMA), a Featured Research Talk by Shelly Sakiyama-Elbert PhD, Vice Dean, UW School of Medicine,…
The Seattle Wellstone Muscular Dystrophy Specialized Research Center is hosting a Distinguished Lecturer at the Breakfast Club seminar series that may be of interest to CTMR folks. Please join us tomorrow for the seminar by Dr. Józef Dulak, University Kraków, Poland, who is visiting Jeff Chamberlain’s Lab as a Fullbright Scholar. If you are interested…
This special event, jointly hosted by the Seattle Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center (MDSRC) and the CTMR, is a fabulous opportunity for researchers and clinicians to connect with the myotonic dystrophy community over food and refreshments. We are thrilled that Dr. John Day will join us from Standford for a research seminar on…
Congratulations to Aditi Prabhala for being selected as a 2024 Husky 100 member! The Husky 100 list recognizes undergraduate and graduate students who make the most of their time at UW. Aditi Prabhala is an undergraduate student in the Regnier Heart and Muscle Mechanics (HAMM) Lab mentored by PhD student, Kerry Kao. In addition to her…
The CTMR is thrilled to be hosting Dr. Andrew McCulloch, Shu Chien Chancellor’s Endowed Chair in Engineering and Medicine, University of California San Diego. Dr. McCulloch will visit us in Seattle tomorrow, May 16th, to present at the Breakfast Club Seminar Series and visit with UW researchers throughout the day. “Andrew is known around the world as…
The CTMR is thrilled to be hosting Dr. Bill Lehman, Professor of Pharmacology, Physiology & Biophysics, Vice Chair Department of Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine. Dr. Lehman will visit us in Seattle tomorrow, April 25th, to present at the Breakfast Club Seminar Series and visit with UW researchers…
Now that the NIH has renewed our UW Center for Translational Muscle Research (CTMR) for another 5 years (!!), we are pleased to announce a Request for Proposals (RFP) to the Pilot Grant program of the CTMR. Applications are due on Wednesday, May 1, 2024, by 5:00 pm. Visit the Pilot Grants page on our…
The CTMR is proud to sponsor the Cardiovascular Research Center, University of Wisconsin-Madison, 2024 Myofilament Meeting: Contractile Systems, Mechanobiology & Regulation: Novel Concepts Technologies & Applications held in Madison, Wisconsin, May 18-21, 2024. CTMR Director, Mike Regnier, is part of the Scientific Organizing Committee for the event, a speaker at the Oral Session on Myofilament-Based…
The CTMR is a Proud Sponsor of the 2024 Cardiac Regulatory Mechanisms Gordon Research Conference Two of our CTMR Directors, Mike Regnier and Jen Davis, will present their research at the conference. And CTMR Investigator, Rong Tian, is co-Chairing the event happening June 23-28, 2024, at Colby-Sawyer College in New London, New Hampshire. Jennifer Davis…
Congratulations to CTMR investigator Dr. Valerie Daggett for being awarded the UW 2023 University Faculty Lecture award! Dr. Daggett will present her work at the 47th annual University Faculty Lecture. Please see the event information below and more information here. Valerie Daggett, PhD David and Nancy Auth Endowed Professor in the Department of Bioengineering Talk…
The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center (MDSRC) at the University of Washington Invites Grant Applications for: Graduate and Postdoctoral Research or Training in Muscular Dystrophies The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center seeks applications from pre- and post-doctoral trainees, or other individuals in mentored training positions in basic,…
The CTMR is thrilled to be hosting Dr. Silvia Blemker, Robert Thomson Distinguished Professor in Biomedical Engineering at the University of Virginia. Dr. Blemker will visit us in Seattle tomorrow, February 29th, to present at the Breakfast Club Seminar Series and visit with UW researchers throughout the day. Please see the details on the flyer…
Congratulations to CTMR faculty investigator Farid Moussavi-Harami, Assistant Professor in the UW Division of Cardiology, for receipt of the Paul F. Cranefield award from the Council of the Society of General Physiologists. The award, reserved for a truly noteworthy paper, is to recognize an independent young investigator who has published an outstanding article in the Journal…
Congratulations to CTMR faculty member Jeff Chamberlain for receipt of the 2024 Muscular Dystrophy Association (MDA) Legacy Award for Achievement in Research. Jeff is a leading investigator in gene therapy for Duchenne muscular dystrophy (DMD). This award is presented for outstanding contributions to translational neuromuscular disease research and will be presented at the 2024 MDA…
Thank you to everyone who presented and attended the CTMR Symposium on December 4th! You all exemplify the rich community of muscle research we have here in Seattle (and beyond). A reminder to please take a moment to provide your feedback on the symposium here. This is a valuable part of our progress reporting for…
The Regnier Lab is hosting Doctoral Candidate, Romi Castillo, from Dr. Jil Tardiff’s lab at the University of Arizona. Romi was a former undergraduate student at UW, and studied the effects of dATP on acto-myosin interactions using the in vitro motility assay with Saffie Mohran in the Regnier Lab. She will be presenting her current…
Please see below for the full schedule of the UW CTMR Annual Symposium. Monday, December 4, 2023, 9:00am – 5:30 pm Pacific Time Orin Smith Auditorium (Building C), SLU, 850 Republican St. Seattle, WA. 98109 United States Full Schedule (please scroll down and click ‘Download’ if the document does not show below):
CTMR Symposium: Monday, December 4th, 2023, 9:00am – 5:30 pm Pacific Time UW SLU Campus, 850 Republican St. Seattle, WA. 98109 United States The Poster Session will begin at 4:10 pm in the C Building Lobby. Please join us for light refreshments, snacks, and great science! Book of Abstracts (please scroll down and click the…
The 4th annual UW Center for Translational Muscle Research (CTMR) symposium will be an all-day event on Monday, December 4th, 2023. See below for the preliminary schedule. Submit your Abstract for the Symposium by November 15th. Please see the information for ABSTRACT SUBMISSION HERE. Please REGISTER HERE by completing the Google Form. When registering you will be able to select in-person or Zoom…
CTMR Investigator Alec Smith, PhD, recently had an R21 funded through the NIAMS that will be looking at developing human stem cell-based models of the muscle spindle for studying proprioceptive function in skeletal muscle. Additionally, he received an Award from the Weill Neurohub to develop models of the neuromuscular junction for studying amyotrophic lateral sclerosis…
Abstract submission is now open for the 4th annual UW Center for Translational Muscle Research (CTMR) symposium that will be held on Monday, December 4th, 2023. To be considered for a poster presentation, abstracts must be submitted by November 15, 2023. Undergraduate students, graduate students, post-docs, research scientists, etc. involved in muscle research, or any related fields are encouraged to submit an abstract….
Registration is now open for our 4th annual UW Center for Translational Muscle Research (CTMR) symposium. This year the symposium will be an all-day event on Monday, December 4th, 2023. We are planning to have an in-person symposium but will also have a Zoom-in option. A preliminary schedule is included below for your reference. Please REGISTER HERE by completing the Google Form. When registering…
The CTMR’s Program Manager, Katie Dickinson, is transitioning to support other programs at UW. We will miss Katie in the CTMR. A big thank you to her for skillfully supporting the CTMR over the past year. We wish her all the best in her future endeavors! We are excited to introduce our new Program Manager…
Towards a More Perfect Union: Multi-Scale Models of Muscle and Their Experimental Validation thematic meeting, which was held in Canterbury, England on July 17-20, 2023. CTMR invited speakers included: Several CTMR graduate students and postdocs presented posters as well.
Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…
Save the date for our 4th annual UW Center for Translational Muscle Research (CTMR) symposium. This year the symposium will be an all-day event on Monday, December 4th, 2023 in Seattle, WA at Orin Smith Auditorium. We are planning to have an in-person symposium but will also have a Zoom-in option. Our Keynote speakers this year will be: Douglas Millay, PhD, is a faculty member…
Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used…
CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…
I am pleased to announce a request for proposals to the Pilot Grant program of the UW Center for Translational Muscle Research (CTMR). Applications are due on Wednesday, February 15, 2023, by 5:00 pm. Visit http://ctmr.washington.edu/pilot-grants/ for more information.
On October 24th, 2022 the CTMR held its annual symposium. Over 130 people registered and researchers from a variety of backgrounds shared their work during our first in-person symposium since the founding of the Center in 2019. CTMR director, Dr, Michael Regnier welcomed scientists from near and far. Although most of the attendees were from…
Please join us in congratulating Eesha Murali on her Washington Research Foundation (WRF) Fellowship!
Momentum in Muscle Research
Save the Date! The 2022 UW CTMR Symposium will be held on Monday, October 24th, 2022 from 9:00am – 6:00pm Pacific Time in the Orin Smith Auditorium. Registration information and additional details coming soon.
In May, CTMR Investigators participated in the 2022 Myofilament research conference “Myofilament Form and Function: Determinants of Sarcomeric Contractility” in Madison, Wisconsin.
A huge congratulations to 2020 CTMR pilot grant recipient Farid Moussavi-Harami, MD, who recently received a Notice of Award for his first NIH R01 grant! An Assistant Professor with the UW Medicine’s Division of Cardiology, Dr. Moussavi Harami’s CTMR pilot grant study focused on the genetic mutations, such as dilated cardiomyopathy, impacted contractile force in…
Research work funded in part by the UW Center for Translational Muscle Research (CTMR) was recently presented at the 66th Biophysical Society Annual Meeting in San Francisco, CA. Congratulations to all presenters!
Join us for the Breakfast Club talk this upcoming Thursday, February 17, 202; 9:00 – 10:00 AM by Dr. Jolanda van der Velden professor and chair at VU University Medical Center, Amsterdam. The talk, hosted by hosted by Dr. Michael Regnier (Dept. of Bioengineering), will occur both in person at the Orin Smith Auditorium, SLU…
Proposals to the Pilot Grant program of the UW Center for Translational Muscle Research (CTMR) are now being accepted. This program supports the development of exciting new muscle research by enabling investigators to obtain preliminary data needed to apply for follow-on funding and receive training in new skills. Funding up to $25,000 (direct costs) is available. Applications are due…
The finalized schedule for the University of Washington Center for Translational Muscle Research (CTMR) symposium is now available. It will be a fully virtual event again this year, via Zoom, on the afternoon of Monday, November 1 (12-5pm PT) and the morning of Tuesday, November 2 (8am-1pm PT). Our Keynote speakers are Rong Tian, Director of the UW Mitochondria…
We are excited to announce that Ruwanthi (Ru) Gunawardane, Ph.D. is joining CTMR as a member of our External Advisory Board. Ru was recently named Executive Director of the Allen Institute for Cell Science in 2020 after spending five years at Amgen, where she worked on assay development for multiple drug targets spanning oncology, inflammation,…
Dr. Nagana Gowda, CTMR Investigator and Research Associate Professor in the Department of Anesthesiology & Pain Medicine, has been awarded an NIH Research Project Grant (R01) thanks in part to CTMR Pilot Grant support. Dr. Gowda’s awarded project is entitled “Quantitative Analysis of Labile Metabolites in Biological Samples” and focuses on addressing the current lack…
Applications are now open for the UW Center for Translational Muscle Research (CTMR) Mini Pilot Grants! Mini Pilot Grants provide $5,000-$10,000 in direct support for pilot studies to new users of CTMR core services who need a limited, specified set of data from one of the cores. Examples of the use of this grant mechanism…
The UW Center for Translational Muscle Research (CTMR) is delighted to announce that three exciting pilot grants have been awarded as part of the 2021 Pilot Grant Program. The CTMR Pilot Grant Program provides funding to support the development of exciting new muscle research on campus by allowing investigators to (1) obtain preliminary data needed…
Registration is now open for the International Society for Heart Research-Journal of Molecular and Cellular Cardiology Webinars coming up in April! Register now using the links below. Please note time zones when registering: webinar times vary to capture audiences in different regions. Can’t join the webinar but still want to watch? All presentations will be…
We are thrilled to share that the CTMR was RENEWED! Here’s to another 5 years of supporting muscle research translational muscle research!
Dr. Christian Mandrycky, a postdoc jointly mentored by CTMR Investigators Mike Regnier & David Mack, was invited to present his work at the Cardiovascular Biology Breakfast Club Seminar Series on the spookiest day of the year– October 31, 2024 — Halloween! Talk Title: Modeling distal arthrogryposis with stem cell derived skeletal muscle Christian brought the Halloween…
Please see the below descriptions of 3 excellent, available postdoc positions in CTMR Investigator Labs. Please consider applying and/or share with your networks! The Regnier Lab invites applications for a postdoctoral fellow to join our cutting-edge research on gene & cell therapy for heart disease. This position offers an exciting opportunity to develop genome-edited induced…
How individuals, labs, centers, and institutions collaborated to produce the first ever computational model showing changes at the protein level manifesting at the protein, sarcomere, cell, tissue, and organ level. A new study made partially possible by the CTMR Quantitative Analysis Core Resources was recently published in the Proceedings of the National Academy of Sciences…
