Accelerating and expanding translational muscle research

The UW Center for Translational Muscle Research (CTMR) is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to provide a unifying organization for muscle research in the heart of Seattle’s biomedical research community.  The goal of the Center is to facilitate new collaborations, recruit new investigators, bring clinicians and researchers together, and provide access to state-of-the-art approaches in multi-scale biomechanics, metabolism, and quantitative-computational analysis, to accelerate translational research efforts at the UW.

Sarcomere Society:

Online bi-weekly seminar series covering current state-of-the-art research related to sarcomere structure and function.

To Subscribe to the Sarcomere Society email list please click here.

Oct 5, 2023

Speaker: Dr. Matthew Childers

Talk Title: Molecular Dynamics simulations to study the structure of the myosin Interacting Heads Motif (IHM)

Nov 30, 2023

Speaker: Dr. Chao Liu

Talk Title: Homologous mutations in β, embryonic, and perinatal muscle myosins have divergent effects on molecular power

Dec 15, 2023

Speaker: Dr. Jia Li

Talk Title: TBA

Latest News

Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle…

CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“…

Resource Cores

Mechanics & Devices Core

The Mechanics and Devices Core provides state-of-the-art measurements of muscle biomechanics at multiple levels of integration, and develops new assays for maturation and assessment of early stage muscle.

Metabolism Core

The Metabolism Core provides tools for in-depth measures and analysis of metabolomics, energetics, cell respiration and mitochondrial function.

Quantitative Analysis Core

The Quantitative Analysis Core provides computational and statistical tools for understanding disease, suggesting new
therapeutic targets, and understanding mechanisms.