Molecular model of myosin.

New Grants Power Muscle Science

Two new grants will accelerate atomic-scale research into the molecular mechanisms of cardiomyopathies. In Autumn 2024, CTMR investigator Matthew Childers was awarded a competitive K99/R00 Pathway to Independence Award from the National Heart, Lung, and Blood Institute of the NIH. Childers’ project combines computational simulations of muscle proteins with stem-cell derived cardiomyocytes to create a…

CTMR to Host Distinguished Lecturer Dr. Jonathan Kirk

CTMR to Host Distinguished Lecturer Dr. Jonathan Kirk

The CTMR is thrilled to host Dr. Jonathan Kirk, Professor and Vice Chair at the Stritch School of Medicine Cell & Molecular Physiology, Loyola University of Chicago on: April 24, 2025, from 9-10am at our Cardiovascular Biology Breakfast Club seminar series. The seminar is available in a hybrid format on Zoom and in person at…

Images of Dr. Mandrycky demonstrating the myosin crossbridge cycle overlay on a diagram of the myosin crossbridge cycle.

Muscle Myosin Makes a Halloween Debut Thanks to CTMR Postdoc Christian Mandrycky!

Dr. Christian Mandrycky, a postdoc jointly mentored by CTMR Investigators Mike Regnier & David Mack, was invited to present his work at the Cardiovascular Biology Breakfast Club Seminar Series on the spookiest day of the year– October 31, 2024 — Halloween!  Talk Title: Modeling distal arthrogryposis with stem cell derived skeletal muscle Christian brought the Halloween…

CTMR Hosting Distinguished Lecturer Steven Schwartz

CTMR Hosting Distinguished Lecturer Steven Schwartz

The CTMR is thrilled to host Dr. Steve Schwartz, Regents Professor of Chemistry and Biochemistry at the University of Arizona at today’s Cardiovascular Biology Breakfast Club seminar series. Dr. Schwartz shares his work on: Theoretical studies of the cardiac thin and thick filament- Structure, the allosteric transmission of mutation and drug mechanism.

Come work with us!

Come work with us!

Please see the below descriptions of 3 excellent, available postdoc positions in CTMR Investigator Labs. Please consider applying and/or share with your networks! The Regnier Lab invites applications for a postdoctoral fellow to join our cutting-edge research on gene & cell therapy for heart disease. This position offers an exciting opportunity to develop genome-edited induced…

Logos and images of institutions, centers, and labs collaborating.

Multiscale collaboration leads to monumental multiscale modeling

How individuals, labs, centers, and institutions collaborated to produce the first ever computational model showing changes at the protein level manifesting at the protein, sarcomere, cell, tissue, and organ level. A new study made partially possible by the CTMR Quantitative Analysis Core Resources was recently published in the Proceedings of the National Academy of Sciences…

Reminder to Register & Submit your Abstract for the CTMR Symposium!

Reminder to Register & Submit your Abstract for the CTMR Symposium!

5th Annual CTMR Symposium WHEN: November 12, 2024, 9:00AM – 6:30PM PT WHERE: UW South Lake Union (SLU) campus (850 Republican St., Seattle, WA, 98109), C Building, Orin Smith Auditorium Please join us for an exciting day of science including a Keynote Session with investigators from the Study of Muscle, Mobility, and Aging (SOMMA), a Featured Research…