Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used to train classifiers. Image © Asencio et al., 2023. See https://doi.org/10.1085/jgp.202213291.”
Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…
5th Annual CTMR Symposium WHEN: November 12, 2024, 9:00AM – 6:30PM PT WHERE: UW South Lake Union (SLU) campus (850 Republican St., Seattle, WA, 98109), C Building, Orin Smith Auditorium Please join us for an exciting day of science including a Keynote Session with investigators from the Study of Muscle, Mobility, and Aging (SOMMA), a Featured Research…
Save the date for our 4th annual UW Center for Translational Muscle Research (CTMR) symposium. This year the symposium will be an all-day event on Monday, December 4th, 2023 in Seattle, WA at Orin Smith Auditorium. We are planning to have an in-person symposium but will also have a Zoom-in option. Our Keynote speakers this year will be: Douglas Millay, PhD, is a faculty member…
Please join us in congratulating Eesha Murali on her Washington Research Foundation (WRF) Fellowship!
Applications are now open for the UW Center for Translational Muscle Research (CTMR) Mini Pilot Grants! Mini Pilot Grants provide $5,000-$10,000 in direct support for pilot studies to new users of CTMR core services who need a limited, specified set of data from one of the cores. Examples of the use of this grant mechanism…
CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…
