2022 Myofilament Meeting
In May, CTMR Investigators participated in the 2022 Myofilament research conference “Myofilament Form and Function: Determinants of Sarcomeric Contractility” in Madison, Wisconsin.


In May, CTMR Investigators participated in the 2022 Myofilament research conference “Myofilament Form and Function: Determinants of Sarcomeric Contractility” in Madison, Wisconsin.


Towards a More Perfect Union: Multi-Scale Models of Muscle and Their Experimental Validation thematic meeting, which was held in Canterbury, England on July 17-20, 2023. CTMR invited speakers included: Several CTMR graduate students and postdocs presented posters as well.
CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…
On October 24th, 2022 the CTMR held its annual symposium. Over 130 people registered and researchers from a variety of backgrounds shared their work during our first in-person symposium since the founding of the Center in 2019. CTMR director, Dr, Michael Regnier welcomed scientists from near and far. Although most of the attendees were from…
Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…
Momentum in Muscle Research
Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used…