2022 Myofilament Meeting

Byctmr1 June 23, 2022June 23, 2022

In May, CTMR Investigators participated in the 2022 Myofilament research conference “Myofilament Form and Function: Determinants of Sarcomeric Contractility” in Madison, Wisconsin.

Saffie Mohran presented “Embryonic myosin mutations T178I & R672C result in mechanical and structural dysfunction in hPSC derived skeletal muscle”.

Farid Mousseri-Harami presented “Dancamtiv reversed negative effects on cardiac myofilament function in the I61Q cTnC mouse model of dilated cardiomyopathy”.

2022 UW CTMR ANNUAL SYMPOSIUM
Bykd August 31, 2022August 31, 2022

Save the Date! The 2022 UW CTMR Symposium will be held on Monday, October 24th, 2022 from 9:00am – 6:00pm Pacific Time in the Orin Smith Auditorium. Registration information and additional details coming soon.

Read More 2022 UW CTMR ANNUAL SYMPOSIUM
Dr. Mike Regnier presents at the Frontiers in Cardiovascular Science Fall seminar series at Stanford! See flyer for details!
Bykd October 28, 2022October 28, 2022

Read More Dr. Mike Regnier presents at the Frontiers in Cardiovascular Science Fall seminar series at Stanford! See flyer for details!
Bykd June 15, 2023June 15, 2023

Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used…

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Applications open for CTMR Mini Pilot Grants!
Byctmr1 July 1, 2021November 21, 2024

Applications are now open for the UW Center for Translational Muscle Research (CTMR) Mini Pilot Grants! Mini Pilot Grants provide $5,000-$10,000 in direct support for pilot studies to new users of CTMR core services who need a limited, specified set of data from one of the cores. Examples of the use of this grant mechanism…

Read More Applications open for CTMR Mini Pilot Grants!
CTMR represents at the 50th European Muscle Conference Florence 2023
Bykd August 15, 2023August 15, 2023

Dr. Mike Regnier is an invited speaker at the 50th European Muscle Conference (EMC) coming up in September 2023. The EMC will be in held in Florence, Italy. Dr. Regnier will be the “DISEASE MODELS” session chair and his talk title will be: “Molecular mechanisms of contractile abnormalities for the MYH7 variant G256E”. Graduate student,…

Read More CTMR represents at the 50th European Muscle Conference Florence 2023
Bykd February 6, 2023February 6, 2023

CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…

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