Congratulations to CTMR Team Core D for their JGP May cover showing “A detailed computational model of striated muscle elucidates how mutations and drugs may alter twitch timing. The spatially explicit model simulates myosin motors connected within a compliant, contractile lattice, complete with thin filament regulation and varying mutation penetrance. The model yields data used to train classifiers. Image © Asencio et al., 2023. See https://doi.org/10.1085/jgp.202213291.”
Towards a More Perfect Union: Multi-Scale Models of Muscle and Their Experimental Validation thematic meeting, which was held in Canterbury, England on July 17-20, 2023. CTMR invited speakers included: Several CTMR graduate students and postdocs presented posters as well.
CTMR/BioCAT collaboration leads to new PNAS paper “Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force“ The UW Center for Translational Muscle Research (CTMR) working with the Regnier Lab and the BioCAT x-ray beamline at the Advanced Photon Source of Argonne National Lab, explore the potential of sarcomere-targeted small molecules as treatments…
Join us for the Breakfast Club talk this upcoming Thursday, February 17, 202; 9:00 – 10:00 AM by Dr. Jolanda van der Velden professor and chair at VU University Medical Center, Amsterdam. The talk, hosted by hosted by Dr. Michael Regnier (Dept. of Bioengineering), will occur both in person at the Orin Smith Auditorium, SLU…
We are excited to announce that Ruwanthi (Ru) Gunawardane, Ph.D. is joining CTMR as a member of our External Advisory Board. Ru was recently named Executive Director of the Allen Institute for Cell Science in 2020 after spending five years at Amgen, where she worked on assay development for multiple drug targets spanning oncology, inflammation,…
The UW Center for Translational Muscle Research (CTMR) is delighted to announce that three exciting pilot grants have been awarded as part of the 2021 Pilot Grant Program. The CTMR Pilot Grant Program provides funding to support the development of exciting new muscle research on campus by allowing investigators to (1) obtain preliminary data needed…
Save the date for our 4th annual UW Center for Translational Muscle Research (CTMR) symposium. This year the symposium will be an all-day event on Monday, December 4th, 2023 in Seattle, WA at Orin Smith Auditorium. We are planning to have an in-person symposium but will also have a Zoom-in option. Our Keynote speakers this year will be: Douglas Millay, PhD, is a faculty member…
